Directors' Holdings

Members	Shares Dec. 31, 2009	Shares Dec. 31, 2008	Options Dec. 31, 2009	Options Dec. 31, 2008
Dr Ernst Ludwig Winnaker, Supervisory Board Chairman, Co-founder	274,476	274,478	0	8,600
Dr Norbert Riedel, Deputy Supervisory Board Chairman	3,300	3,300	0	5,590
Dr Pol Bamelis, Supervisory Board member	400	400	0	0
Sebastian Freitag, Supervisory Board member	2,500	2,500	0	0
Dr Mathias Albert Boehringer Supervisory Board member	0	0	0	0
Total Supervisory Board	280,676	280,676	0	14,190
Dr Peter Heinrich, Chief Executive Officer (until April 29, 2009), Co-founder	- ^*)	505,505	210,000	246,636
Dr Frank Mathias Chief Executive Officer (since April 29, 2009) Chief Operating Officer (until April 29, 2009)	0	0	57,500	22,500
Dr Thomas Klaue, Chief Financial Officer	4,500	4,500	65,833	38,333
Dr Axel Mescheder (from May 19, 2008), Chief Medical Officer & Chief Developement Officer (until December 10, 2009)	6,000	6,000	81,686	62,836
Total Executive Board	10,500	516,005	415,019	370,305
Treasury Stock	0	0	0	0

^*) No data as at closing date