Directors' Holdings

Members Shares
Dec. 31,
2010		 Shares
Dec. 31,
2009		 Options
Dec. 31,
2010		 Options
Dec. 31,
2009
Dr Ernst Ludwig Winnaker,
Supervisory Board Chairman, Co-founder		 274,476 274,478 0 0
Dr Norbert Riedel,
Deputy Supervisory Board Chairman		 3,300 3,300 0 0
Dr Pol Bamelis,
Supervisory Board member		 400 400 0 0
Sebastian Freitag,
Supervisory Board member (until Sept. 30, 2010)		 2,500 2,500 0 0

Dr Mathias Albert Boehringer
Supervisory Board member

 0 0 0 0
Dr Thomas Werner
Supervisory Board member (since Feb. 2, 2010)		 0 0 0 0
Total Supervisory Board 280,676 280,676 0 0
Dr Frank Mathias
Chief Executive Officer		 2,000 0 92,500 57,500
Dr Thomas Klaue,
Chief Financial Officer (until April 17, 2010)		 4,500 4,500 77,513 65,833
Arnd Christ
Chief Financial Officer (since April 17, 2010)		 0 - 14,278 -
Total Executive Board 6,500 4,500 184,291 123,333
Treasury Stock 0 0 0 0